Synthesis of 6-Piperazinyl-3,4-dihydroquinazolin-2(1H)-ones

Sulfuric Acid Functionalized Magnetic Nanocatalyst for One-pot Green Synthesis of 2,3-Dihydroquinazolin-4 (1H) -ones

Sulfuric acid functionalized magnetic nanocatalyst (SAMNC) has been prepared as an efficientacidic and applied in the one-pot preparation of 2,3-dihydroquinazolin-4 (1H) -one derivatives.This catalyst has been characterized by FT-IR, SEM, and VSM. According to the obtainedresults, including time, yield and recyclability, SAMNC could be considered as an efficient catalystfor organic transformati...

The Synthesis and Evaluation of Dihydroquinazolin-4-ones and Quinazolin-4-ones as Thyroid Stimulating Hormone Receptor Agonists.

We herein describe the rapid synthesis of a diverse set of dihydroquinazolin-4-ones and quinazolin-4-ones, their biological evaluation as thyroid stimulating hormone receptor (TSHR) agonists, and SAR analysis. Among the compounds screened, 8b was 60-fold more potent than the hit compound 1a, which was identified from a high throughput screen of over 73,000 compounds.

Boric Acid Supported on Montmorillonites as Catalysts for Synthesis of 2,3-dihydroquinazolin-4(1H)-ones

Synthesis of 2,3-dihydroquinazolin-4(1H)-ones using H3BO3/montmorillonite K10 (H3BO3/mont K10) catalyst has been reported. H3BO3/mont K10 and H3BO3/mont K30 have been prepared and used as catalysts in the reaction between anthranilamide and benzaldehyde to prepare 2-phenyl...

Novel and cost-effective biocatalyst consisting of nanofibrillated cellulose and TiCl3 for the synthesis of 2,3'-dihydroquinazolin-4-(1H)-ones

A novel and cost-effective catalyst for synthesis of 2,3'-dihydroquinazolin-4-(1H)-ones was developed utilizing a combined nanocomposite obtained from bonding TiCl3 to hydroxyl groups of nanofibrillated cellulose as a green and inexpensive support.The structure of the catalyst was investigated using the Fourier transform infrared spectroscopy (FT-IR), field emission scanning...

synthesis of 2,3-dihydroquinazolin-4(1h)-ones catalyzed by malonic acid as efficient catalyst